What it is: BiomeFx uses the best of current technology to give you insights on the microbial diversity and functional health of the gut.
This item includes a test kit and a 60 min consultation to review lab results.
If you would like an in-depth 1-hour consultation to cover your results and give you specific recommendations, please order the test kit+consulation here.
The kit includes:
• Easy directions, collection vial, and utensils
• Requisition form for patient information, pertinent supplements, medications, and a health questionnaire
• Sealable return packaging
Why It’s Unique
Stool testing has become a popular method for evaluating the status of an individuals’ microbiome. The problem is that many of these tests are often lacking in accuracy, reliability, and functionality. BiomeFx not only uses the most advanced and accurate sequencing technology, but it also explores some of the many inner functions of the gut microbiome.
This test will explore the pathogens in your gut as well as the keystone species that are crucial to overall health and the metabolic functions that rely on the gut microbiome.
With these insights, you can then use the actionable nutrition, lifestyle, and supplement recommendations as a road map for improving your unique gut microbiome. This is the future of microbiome assessment and analysis.
Diversity is Key
When talking about diversity in an ecological setting, there are two types of diversity: alpha- and beta-diversity. In ecology, alpha-diversity refers to the average diversity of species in a particular ecosystem. This marker reflects your own personal species diversity within your gut microbiome – aka how many different types of bacteria that are present. A robust number of bacterial species is linked to better health and a more resilient microbiome, which is why alpha-diversity is a key factor when assessing overall health and longevity.
Beta-diversity is the variation of species when comparing two separate ecosystems. This marker reflects the overall diversity of your gut microbiome as compared to a healthy population. This is an important reference marker because you could have great diversity within your own microbiome, but you could have low beta-diversity when compared with healthy populations. This would indicate that microbial diversity should be a priority for you going forward. Taking a closer look at your keystone species can provide useful insight into improving your beta-diversity. The goal is never perfection but progress.
Looking at your Microbiome’s Resilience
The Resistome Occurrence Index is a measure of richness and stability within your gut microbiome. It is also a measure of the overall resilience and strength of the microbiome. In the microbiome, bacteria can produce natural anti-microbials and chemicals to compete with one another through a process called competitive exclusion. A low index suggests that you have low richness and resilience in your gut. A stronger and more diverse gut microbiome will be more resilient against gut-damaging factors. The more resilient your microbiome becomes, the more it can withstand healthy competition amongst a variety of bacterial and fungal species. If there is insufficient competition within the gut microbiome, this can indicate that the ecology of the gut is out of balance. Just as a sailboat cannot sail without the resistance of the wind, the gut microbiome cannot function to protect the human host without healthy microbial competition in the gut.
How to Address Gut Infections
BiomeFx analyzes over 25 pathogens and measures their relative abundance as a percentage of your entire microbiome. This is different from traditional stool tests looking for any detectable number of pathogens present. While it isn’t uncommon to have a small number of pathogens present in your microbiome, the relative abundance in proportion to your other bacteria is what’s important. A strong microbiome is equipped with both strong competition among species and resilient keystone strains to maintain a healthy environment. This healthy competition is just one of the factors that helps to keep pathogens in check.
By evaluating multiple aspects of microbial balance, strength, and resilience, BiomeFx is able to provide a customized plan to re-balance pathogen occurrence. It is also worth noting that older technologies have a high rate of false positives when it comes to pathogen detection due to the limitations of their sequencing methods. This is just part of the reason why whole genome sequencing is the most accurate technology on the market.
How your Microbiome Functions
We have co-evolved with microbes in our gastrointestinal tract for millions of years, and during that time, a symbiotic relationship has developed. The interaction between the microbial populations and human metabolic processes is one of great scientific interest. Linking the bridge between bacterial populations and human health is at the forefront of creating personalized medicine.
Researchers are beginning to understand how the microbiome influences hormone balance, neurotransmitters, autoimmunity, detoxification, digestion, and disease risk. One of the most unique aspects of BiomeFX (in partnership with CosmosID) is the ability to evaluate the influence of the gut microbiome on disease risk. With the most robust database of healthy samples, BiomeFx can help you identify early deviation from a healthy population.
This is a functional test to determine the overall diversity of the gut microbiome, key microbe ratios, and other functional criteria.
This is is not a diagnostic test – yet a valuable tool to see how well your gut is functioning, and more importantly, how it is responding to your diet and lifestyle protocol.
***Important notes about lab kits for purchased above***
- We are unable to ship lab kits to PO boxes. Please use a residential address.
- Some lab providers fill out requisition forms ahead of time, with patient information. To avoid confusion when processing orders, if you are ordering lab kits for multiple people, we do request that you place a separate order for each person. Also, if placing an order for another person please specify who the test is for in the notes when checking out.
- Please note: after you order a test kit, getting the lab draw and/or completing the test is your responsibility.
- It is also your responsibility to have the test interpreted by a qualified professional
- Due to the fees we incur after a test kit is sent, we are unable to offer returns or exchanges on test kits.
- Once you have sent in your lab kit, the lab will send us test results which we will forward to you.
- Please allow 4-6 for the lab to process your results once they are received by the lab
There will be an additional shipping fee for International lab orders, which varies by location. Once your order is received, we will email you in regards to the additional cost, to be paid via invoice.